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MMAD (Demethyldolastatin 10)

whakatauranga:
5.00 i roto i te 5 hāngai ana i runga i 1 whakatauranga kiritaki
SKU: 203849-91-6. Kāwai:

Ko te AASraw ko te whakawhitinga me te whakaputa i te kaha mai i te kararangi ki te huinga papatipu MMAD (Demethyldolastatin 10) (CAS 203849-91-6), i raro i te ture CGMP me te pūnaha whakahaere kounga.

I tua atu, MMAD Kei te korerohia kia whakamahia i roto i te hanganga o nga whakawhitinga taraiwa antibody antibody (NDCs). I nga NDC, ka honohia te MMAD ki te antibody 5T4 ranei antibody Her2. E whakaatuhia ana ko nga NDC te whakaatu i te kaha ake me te mahi rongoha.

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MMAD (Demethyldolastatin 10) ataata


MMAD (Demethyldolastatin 10) Pūāhua taketake

ingoa: MMAD (Demethyldolastatin 10)
CAS: 203849-91-6
Tātai rāpoi: C41H66N6O6S
Taumaha Taumaha: 771.06
Te Poari Maka: N / He
Tiaki Tārua: Powder -20 ° C 3 tau
4 ° C 2 tau
I roto i nga marama -80 ° C 6 marama
-20 ° C 1 marama
tae: White ki te-maama (pakari)


MMAD (Demethyldolastatin 10) (203849-91-6) whakamahi i te huringa steroids

ingoa

Ngā Synonyms: Demethyldolastatin 10 (203849-91-6); Monomethylauristatin D; Monomethyl Dolastatin 10
Chemical Name: (S)-N-((3R,4S,5S)-3-methoxy-1-((S)-2-((1R,2R)-1-methoxy-2-methyl-3-oxo-3-(((S)-2-phenyl-1-(thiazol-2-yl)ethyl)amino)propyl)pyrrolidin-1-yl)-5-methyl-1-oxoheptan-4-yl)-N,3-dimethyl-2-((S)-3-methyl-2-(methylamino)butanamido)butanamide

Whakatupato i te MMAD (Demethyldolastatin 10)

Kāore i tino tika te hua mo nga tono hauora. Mo te rangahau anake

Mo te whiwhi i te whakahekenga nui ake, whakamahanahia te ngongo i te 37 ℃ me te ruiruu i te pati ultrasonic mo te wa.Ka taea te penapena i raro i te -20 ℃ mo etahi marama.

Nga tohutohu

I roto i te Vitro: Ko te MMAD (Demethyldolastatin 10) (203849-91-6) ka honoa i roto i te tukanga oxime-ligation tuumui hei whakaputa i etahi kaitautoko antibody-drug homogenous (ADCs) me te ōwehenga-a-antibody o ~ 2.0. Ko nga kaitohu hua e whakaatu ana i nga tohu rongoora, o nga mahi hauora i roto i te vitioxicxicity ki te HER2 + pukupuku pukupuku. Ina whakaritea ana ki nga ADC i hangaia e te cysteine ​​alkylation i muri i te whakaheke i te whakawhitinga i waenga i te tangata, ka whakaatuhia he nui te whakawhitinga o te ADC me te waikawa-aa-waikawa-a-waikawa me te waikawa-aa-waikawa-i te vitroxicity

I roto i te Vivi: Ka whakaatuhia e nga kaitautoko antibody-drug medications (ADCs) te whakahekenga o te tumuaki katoa i roto i te kiore. He pai ake hoki te tohu o te toxicology i roto i nga kiore.


Me pehea te hoko MMAD; hoko Demethyldolastatin 10 mai i AASraw

1.Me whakapiri mai ki a maatau i ta maatau īmēra pūnaha uiuinga, te rangiperangi raneikaihoko ratonga kiritaki (TKT).
2.Me homai ki a matou to nui me to korero.
Ka hoatu e 3.Our TKT ki a koe te korero, te wa utu, te tau aroturuki, nga huarahi tuku, me te raketanga o te taenga mai (ETA).
4.Pairanga ka mahia, ka tukuna atu nga taonga i nga haora 12 (Mo te ota i roto i te 10kg).
5.Goods i whakawhiwhia me te tuku korero.


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