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Trilostane Powder (13647-35-3)

whakatauranga: SKU: 13647-35-3. Kāwai:

Ko te AASraw kei te waihanga me te kaha hanga mai i te karamu ki te raupapa papatipu o te Trilostane Powder (13647-35-3), i raro i te ture CGMP me te punaha whakahaere kounga kounga.

Whakaahuatanga Hua

Trilostane Powder (13647-35-3) ataata


Trilostane Powder (13647-35-3) Specification:

Te Hanganga Matū: ingoa hua: Trilostane
Cas No.: 13647-35-3
Tātai rāpoi: C20H27NO3
Taumaha rāpoi: 329.43
Paerewa: I roto i te whare
rokiroki: Te pouri, te pouri me te 0 - 4 C mo te wa poto (ra ki nga wiki) ranei -20 C mo te wa roa (marama ki te tau).
Tuhinga (COA & HPLC etc.): wātea

Trilostane Powder (13647-35-3) DTuhinga:

Ko te paura trilostane ko te kaitautoko o te dehydrogenase 3β-hydroxysteroid e whakamahia ana i te maimoatanga o te mamae Cache me te hyperaldosteronism tuatahi. Ko nga mate e rua nei ka hua te nui o nga homoni corticosteroid i roto i te tinana. He mea nui te Corticosteroid mo te tinana ki te whakamahi i nga warowaihā, te ngako me nga pūmua, me te urupare noa ki te ahotea. He tika hoki mo te whakaritenga o te tote me te wai toenga i roto i te tinana. Ko te paura trilostane ka awhina i te aukati i te mahi o corticosteroids, hei whakahaere i nga tohu e pa ana ki enei turoro.

Ko te paura trilostane ka taea hoki te whai hua ki te maimoatanga o te mate pukupuku o te uma i pa ki nga wahine i haere i te menopause.

I mua i whakaaetia i te tau 2008 mo te maimoatanga o te mate Cush (hyperandrenocorticism) i roto i nga kuri. Koinei hoki te rongoa tuatahi i whakaaetia ki te hamani e rua ko te pituitary- me te kuri-i runga i nga kuri a adrenal-e whakawhirinaki ana. Ka mahi tenei tarukino tohutao ma te aukati i te hanga cortisol i roto i nga hiko adrenal.

tohutoro:

  • 1: Midence JN, Drobatz KJ, Hess RS. Ko nga Whakatuturutanga Cortisol i nga Kuri-Ka Whakanohia Ana me Hyperadrenocorticism i tukinotia me Trilostane. J Vet Wahanga Med. 2015 Nov; 29 (6): 1529-33. doi: 10.1111 / jvim.13615. Epub 2015 Sep 16. PubMed PMID: 26374943.
  • 2: Fracassi F, Corradini S, Floriano D, Boari A, Aste G, Pietra M, Bergamini PF, Dondi F. Nga mea pono e ora ana i roto i nga kuri me te hypercortisolism e whakawhirinaki ana-pituitary i tukinotia me te trilostane. Reta Tekau. 2015 Jan 10; 176 (2): 49. doi: 10.1136 / vr.102546. Epub 2014 Aug 28. PubMed PMID: 25170036.
  • 3: Bonadio CM, Feldman EC, Cohen TA, Kass PH. Ko te Whakataurite o te whakamatautau whakamātautau whakaohooho a adrenocorticotropic i timata 2 maatau ki te 4 haora i muri i te whakahaere trilostane i nga kuri me te hyperadrenocorticism tupu noa. J Vet Wahanga Med. 2014 Jul-Aug; 28 (4): 1239-43. doi: 10.1111 / jvim.12357. Epub 2014 May 26. PubMed PMID: 24863172.

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